FOXO1 couples metabolic activity and growth state in the vascular endothelium

Endothelial cells (ECs) are plastic cells that can switch between growth states with different bioenergetic and biosynthetic requirements(1). Although quiescent in most healthy tissues, ECs divide and migrate rapidly upon proangiogenic stimulation(2,3). Adjusting endothelial metabolism to growth sta...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Wilhelm, Kerstin, Happel, Katharina, Eelen, Guy, Schoors, Sandra, Oellerich, Mark F., Lim, Radiance, Zimmermann, Barbara, Aspalter, Irene M., Franco, Claudio A., Boettger, Thomas, Braun, Thomas, Fruttiger, Marcus, Rajewsky, Klaus, Keller, Charles, Brüning, Jens C., Gerhardt, Holger, Carmeliet, Peter, Potente, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380221/
https://ncbi.nlm.nih.gov/pubmed/26735015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16498
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