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miR-1/133a Clusters Cooperatively Specify the Cardiomyogenic Lineage by Adjustment of Myocardin Levels during Embryonic Heart Development

miRNAs are small RNAs directing many developmental processes by posttranscriptional regulation of protein-coding genes. We uncovered a new role for miR-1-1/133a-2 and miR-1-2/133a-1 clusters in the specification of embryonic cardiomyocytes allowing transition from an immature state characterized by...

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Detalhes bibliográficos
Main Authors: Wystub, Katharina, Besser, Johannes, Bachmann, Angela, Boettger, Thomas, Braun, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777988/
https://ncbi.nlm.nih.gov/pubmed/24068960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003793
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