Sirtuin 1 (Sirt1) Overexpression in BaF3 Cells Contributes to Cell Proliferation Promotion, Apoptosis Resistance and Pro-Inflammatory Cytokine Production

BACKGROUND: B lymphocyte hyperactivity is a main characteristic of systemic lupus erythematosus (SLE), and B lymphocytes play a prominent pathogenic role in the development and progression of SLE. The aim of this study was to investigate the role of Sirtuin 1 (Sirt1) in B lymphocytes. MATERIAL/METHO...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Wang, Qian, Yan, Chao, Xin, Miaomiao, Han, Li, Zhang, Yunqing, Sun, Mingshu
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2017
Schlagworte:
Lab/In Vitro Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380195/
https://ncbi.nlm.nih.gov/pubmed/28346398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.900754
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