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Nicotinamide Inhibits Glycolysis of HL-60 Cells by Modulating Sirtuin 1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Coactivator 1α (PGC-1α)/Hypoxia-Inducible Factor-2α (HIF2α) Signaling Pathway
BACKGROUND: Nicotinamide can affect differentiation and proliferation of leukemia cells. This research aimed to explore the regulatory effect of nicotinamide on glycolysis metabolism of leukemia cells and to clarify the associated mechanisms. MATERIAL/METHODS: HL-60 cells were treated with nicotinam...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Med Sci Monit |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
International Scientific Literature, Inc.
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7282349/ https://ncbi.nlm.nih.gov/pubmed/32469848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.920810 |
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