Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH)

The practice of treating PAH patients with oral or intravenous sildenafil suffers from the limitations of short dosing intervals, peripheral vasodilation, unwanted side effects, and restricted use in pediatric patients. In this study, we sought to test the hypothesis that inhalable poly(lactic-co-gl...

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Veröffentlicht in:J Control Release
Hauptverfasser: Rashid, Jahidur, Patel, Brijeshkumar, Nozik-Grayck, Eva, McMurtry, Ivan F., Stenmark, Kurt R, Ahsan, Fakhrul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380153/
https://ncbi.nlm.nih.gov/pubmed/28185800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.02.003
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