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Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ
The proinflammatory cytokine IL-36γ is highly expressed in epithelial cells and is a pivotal mediator of epithelial inflammation. In particular, IL-36γ is strongly associated with the inflammatory skin disease psoriasis. As with other IL-1 cytokines, IL-36γ is expressed as an inactive precursor and...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5380102/ https://ncbi.nlm.nih.gov/pubmed/28289191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620954114 |
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