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Cathepsin G cleaves and activates IL-36γ and promotes the inflammation of psoriasis
BACKGROUND: IL-36γ is considered to be a valuable biomarker in psoriatic patients, which is expressed as an inactive precursor that needs to be proteolytically processed and activated, and neutrophil-derived proteases seemed to be potent activating enzymes of IL-36γ. OBJECTIVES: This study aims to i...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372007/ https://ncbi.nlm.nih.gov/pubmed/30804664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S194765 |
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