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Ultraviolet B Inhibits IL-17A/TNF-α-Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts
BACKGROUND: Psoriasis is a chronic immune-mediated inflammatory disease, and a mixed Th1/Th17 cytokine environment plays a critical role in the pathogenesis of psoriasis. Dermal fibroblasts secrete certain cytokines such as IL-6, IL-8, and CXCL-1, contributing to the hyperproliferative state of the...
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出版年: | Front Immunol |
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主要な著者: | , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Frontiers Media S.A.
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289959/ https://ncbi.nlm.nih.gov/pubmed/28217129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00091 |
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