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Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by direct coupling analysis

Proteins have evolved to perform diverse cellular functions, from serving as reaction catalysts to coordinating cellular propagation and development. Frequently, proteins do not exert their full potential as monomers but rather undergo concerted interactions as either homo-oligomers or with other pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Uguzzoni, Guido, John Lovis, Shalini, Oteri, Francesco, Schug, Alexander, Szurmant, Hendrik, Weigt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380090/
https://ncbi.nlm.nih.gov/pubmed/28289198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615068114
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