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Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by direct coupling analysis

Proteins have evolved to perform diverse cellular functions, from serving as reaction catalysts to coordinating cellular propagation and development. Frequently, proteins do not exert their full potential as monomers but rather undergo concerted interactions as either homo-oligomers or with other pr...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Uguzzoni, Guido, John Lovis, Shalini, Oteri, Francesco, Schug, Alexander, Szurmant, Hendrik, Weigt, Martin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380090/
https://ncbi.nlm.nih.gov/pubmed/28289198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615068114
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