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Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by direct coupling analysis
Proteins have evolved to perform diverse cellular functions, from serving as reaction catalysts to coordinating cellular propagation and development. Frequently, proteins do not exert their full potential as monomers but rather undergo concerted interactions as either homo-oligomers or with other pr...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5380090/ https://ncbi.nlm.nih.gov/pubmed/28289198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615068114 |
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