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Direct-Coupling Analysis of nucleotide coevolution facilitates RNA secondary and tertiary structure prediction

Despite the biological importance of non-coding RNA, their structural characterization remains challenging. Making use of the rapidly growing sequence databases, we analyze nucleotide coevolution across homologous sequences via Direct-Coupling Analysis to detect nucleotide-nucleotide contacts. For a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: De Leonardis, Eleonora, Lutz, Benjamin, Ratz, Sebastian, Cocco, Simona, Monasson, Rémi, Schug, Alexander, Weigt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666395/
https://ncbi.nlm.nih.gov/pubmed/26420827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv932
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