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Direct-Coupling Analysis of nucleotide coevolution facilitates RNA secondary and tertiary structure prediction
Despite the biological importance of non-coding RNA, their structural characterization remains challenging. Making use of the rapidly growing sequence databases, we analyze nucleotide coevolution across homologous sequences via Direct-Coupling Analysis to detect nucleotide-nucleotide contacts. For a...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666395/ https://ncbi.nlm.nih.gov/pubmed/26420827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv932 |
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