Mouse cytomegalovirus M36 and M45 death suppressors cooperate to prevent inflammation resulting from antiviral programmed cell death pathways

The complex interplay between caspase-8 and receptor-interacting protein (RIP) kinase RIP 3 (RIPK3) driving extrinsic apoptosis and necroptosis is not fully understood. Murine cytomegalovirus triggers both apoptosis and necroptosis in infected cells; however, encoded inhibitors of caspase-8 activity...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Daley-Bauer, Lisa P., Roback, Linda, Crosby, Lynsey N., McCormick, A. Louise, Feng, Yanjun, Kaiser, William J., Mocarski, Edward S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380087/
https://ncbi.nlm.nih.gov/pubmed/28292903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616829114
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