The Human Cytomegalovirus UL36 Gene Controls Caspase-Dependent and -Independent Cell Death Programs Activated by Infection of Monocytes Differentiating to Macrophages

The cellular protease caspase-8 activates extrinsic apoptosis and also functions to promote monocyte-to-macrophage differentiation. Differentiation-induced alterations to antiviral caspase-8-dependent cell death pathways are unclear. Here, we show THP-1 monocyte-to-macrophage differentiation alters...

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Detalles Bibliográficos
Autores principales: McCormick, A. Louise, Roback, Linda, Livingston-Rosanoff, Devon, St. Clair, Courtney
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863825/
https://ncbi.nlm.nih.gov/pubmed/20219915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01345-09
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