Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ

The peroxisome proliferator-activated receptor (PPAR) family comprises three subtypes: PPARα, PPARγ, and PPARδ. PPARδ transcriptionally modulates lipid metabolism and the control of energy homeostasis; therefore, PPARδ agonists are promising agents for treating a variety of metabolic disorders. In t...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Wu, Chyuan-Chuan, Baiga, Thomas J., Downes, Michael, La Clair, James J., Atkins, Annette R., Richard, Stephane B., Fan, Weiwei, Stockley-Noel, Theresa A., Bowman, Marianne E., Noel, Joseph P., Evans, Ronald M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2017
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PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380080/
https://ncbi.nlm.nih.gov/pubmed/28320959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621513114
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