PPARδ Promotes Running Endurance by Preserving Glucose

Management of energy stores is critical during endurance exercise, with a shift in substrate utilization from glucose towards fat being a hallmark of trained muscle. Here we show that this key metabolic adaptation is both dependent on muscle PPARδ and stimulated by PPARδ ligand. Furthermore, we find...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Fan, Weiwei, Waizenegger, Wanda, Lin, Chun Shi, Sorrentino, Vincenzo, He, Ming-Xiao, Wall, Christopher E., Li, Hao, Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Auwerx, Johan, Downes, Michael, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492977/
https://ncbi.nlm.nih.gov/pubmed/28467934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.04.006
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