AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program

Basal-like breast cancer (BLBC) is associated with high-grade, distant metastasis and poor prognosis. Elucidating the determinants of aggressiveness in BLBC may facilitate the development of novel interventions for this challenging disease. In this study, we show that aldo-keto reductase 1 member B1...

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Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Wu, Xuebiao, Li, Xiaoli, Fu, Qiang, Cao, Qianhua, Chen, Xingyu, Wang, Mengjie, Yu, Jie, Long, Jingpei, Yao, Jun, Liu, Huixin, Wang, Danping, Liao, Ruocen, Dong, Chenfang
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379972/
https://ncbi.nlm.nih.gov/pubmed/28270406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160903
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