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An engineered minimal chromosomal passenger complex reveals a role for INCENP/Sli15 spindle association in chromosome biorientation

The four-subunit chromosomal passenger complex (CPC), whose enzymatic subunit is Aurora B kinase, promotes chromosome biorientation by detaching incorrect kinetochore–microtubule attachments. In this study, we use a combination of truncations and artificial dimerization in budding yeast to define th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Fink, Sarah, Turnbull, Kira, Desai, Arshad, Campbell, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379952/
https://ncbi.nlm.nih.gov/pubmed/28314741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609123
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