Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics

Dynamic microtubules facilitate chromosome arrangement before anaphase, whereas during anaphase microtubule stability assists chromosome separation. Changes in microtubule dynamics at the metaphase–anaphase transition are regulated by Cdk1. Cdk1-mediated phosphorylation of Sli15/INCENP promotes prea...

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Detalhes bibliográficos
Main Authors: Nakajima, Yuko, Cormier, Anthony, Tyers, Randall G., Pigula, Adrianne, Peng, Yutian, Drubin, David G., Barnes, Georjana
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135399/
https://ncbi.nlm.nih.gov/pubmed/21727193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009137
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