Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics

Dynamic microtubules facilitate chromosome arrangement before anaphase, whereas during anaphase microtubule stability assists chromosome separation. Changes in microtubule dynamics at the metaphase–anaphase transition are regulated by Cdk1. Cdk1-mediated phosphorylation of Sli15/INCENP promotes prea...

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Détails bibliographiques
Auteurs principaux: Nakajima, Yuko, Cormier, Anthony, Tyers, Randall G., Pigula, Adrianne, Peng, Yutian, Drubin, David G., Barnes, Georjana
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2011
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135399/
https://ncbi.nlm.nih.gov/pubmed/21727193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009137
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