Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics

Dynamic microtubules facilitate chromosome arrangement before anaphase, whereas during anaphase microtubule stability assists chromosome separation. Changes in microtubule dynamics at the metaphase–anaphase transition are regulated by Cdk1. Cdk1-mediated phosphorylation of Sli15/INCENP promotes prea...

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Main Authors: Nakajima, Yuko, Cormier, Anthony, Tyers, Randall G., Pigula, Adrianne, Peng, Yutian, Drubin, David G., Barnes, Georjana
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2011
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135399/
https://ncbi.nlm.nih.gov/pubmed/21727193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009137
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