Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics

Dynamic microtubules facilitate chromosome arrangement before anaphase, whereas during anaphase microtubule stability assists chromosome separation. Changes in microtubule dynamics at the metaphase–anaphase transition are regulated by Cdk1. Cdk1-mediated phosphorylation of Sli15/INCENP promotes prea...

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Autori principali: Nakajima, Yuko, Cormier, Anthony, Tyers, Randall G., Pigula, Adrianne, Peng, Yutian, Drubin, David G., Barnes, Georjana
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2011
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135399/
https://ncbi.nlm.nih.gov/pubmed/21727193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009137
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