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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study. To illuminate the combinations of ingredients most important to align and segregate chromosomes and simultaneously assemble a bipolar spindle,...

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Pubblicato in:eLife
Autori principali: Edelmaier, Christopher, Lamson, Adam R, Gergely, Zachary R, Ansari, Saad, Blackwell, Robert, McIntosh, J Richard, Glaser, Matthew A, Betterton, Meredith D
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311174/
https://ncbi.nlm.nih.gov/pubmed/32053104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48787
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