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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study. To illuminate the combinations of ingredients most important to align and segregate chromosomes and simultaneously assemble a bipolar spindle,...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Edelmaier, Christopher, Lamson, Adam R, Gergely, Zachary R, Ansari, Saad, Blackwell, Robert, McIntosh, J Richard, Glaser, Matthew A, Betterton, Meredith D
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311174/
https://ncbi.nlm.nih.gov/pubmed/32053104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48787
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