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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study. To illuminate the combinations of ingredients most important to align and segregate chromosomes and simultaneously assemble a bipolar spindle,...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Edelmaier, Christopher, Lamson, Adam R, Gergely, Zachary R, Ansari, Saad, Blackwell, Robert, McIntosh, J Richard, Glaser, Matthew A, Betterton, Meredith D
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311174/
https://ncbi.nlm.nih.gov/pubmed/32053104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48787
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