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Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression

The chromosomal passenger complex (CPC), composed of inner centromere protein (INCENP), Survivin, Borealin, and the kinase Aurora B, contributes to the activation of the mitotic checkpoint. The regulation of CPC function remains unclear. Here, we reveal that in addition to Survivin and Borealin, the...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Wheelock, Michael S., Wynne, David J., Tseng, Boo Shan, Funabiki, Hironori
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379950/
https://ncbi.nlm.nih.gov/pubmed/28314740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609061
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