Dual Detection of Chromosomes and Microtubules by the Chromosomal Passenger Complex Drives Spindle Assembly

Chromosome-dependent spindle assembly requires the chromosomal recruitment and activation of Aurora B, the kinase subunit of the chromosomal passenger complex (CPC). It remains unclear how the chromosome-activated kinase spatially transmits signals to organize the micron scale spindle. Here we revea...

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Bibliographic Details
Main Authors: Tseng, Boo Shan, Tan, Lei, Kapoor, Tarun M., Funabiki, Hironori
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905387/
https://ncbi.nlm.nih.gov/pubmed/20627073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.018
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