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Structural analysis of the role of TPX2 in branching microtubule nucleation

The mitotic spindle consists of microtubules (MTs), which are nucleated by the γ-tubulin ring complex (γ-TuRC). How the γ-TuRC gets activated at the right time and location remains elusive. Recently, it was uncovered that MTs nucleate from preexisting MTs within the mitotic spindle, which requires t...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Autores principales: Alfaro-Aco, Raymundo, Thawani, Akanksha, Petry, Sabine
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379942/
https://ncbi.nlm.nih.gov/pubmed/28264915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607060
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