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Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2

The microtubules that comprise mitotic spindles in animal cells are nucleated at centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin. Indirect evidence also has suggested that microtubules might be nucleated from pre-existing microtubules throughout the spindl...

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Bibliographic Details
Main Authors: Petry, Sabine, Groen, Aaron C., Ishihara, Keisuke, Mitchison, Timothy J., Vale, Ronald D.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680348/
https://ncbi.nlm.nih.gov/pubmed/23415226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.044
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