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Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2

The microtubules that comprise mitotic spindles in animal cells are nucleated at centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin. Indirect evidence also has suggested that microtubules might be nucleated from pre-existing microtubules throughout the spindl...

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Autors principals: Petry, Sabine, Groen, Aaron C., Ishihara, Keisuke, Mitchison, Timothy J., Vale, Ronald D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680348/
https://ncbi.nlm.nih.gov/pubmed/23415226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.044
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