Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair

BACKGROUND: Resistance to platinum-based chemotherapy remains a great challenge for ovarian cancer treatment. The human let-7 family contains 13 members located on nine different chromosomes, and most members have been implicated in the modulation of drug sensitivity in cancers. Our previous study s...

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Detalhes bibliográficos
Publicado no:J Ovarian Res
Main Authors: Xiao, Man, Cai, Jing, Cai, Liqiong, Jia, Jinghui, Xie, Lisha, Zhu, Ying, Huang, Bangxing, Jin, Dongdong, Wang, Zehua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379542/
https://ncbi.nlm.nih.gov/pubmed/28376831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-017-0321-8
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