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Transcription factor ZBP-89 drives a feedforward loop of β-catenin expression in colorectal cancer

In colorectal cancer (CRC), APC-mediated induction of unregulated cell growth involves post-translational mechanisms that prevent proteasomal degradation of proto-oncogene β-catenin (CTNNB1) and its eventual translocation to the nucleus. However, about 10 percent of colorectal tumors also exhibit in...

詳細記述

保存先:
書誌詳細
出版年:Cancer Res
主要な著者: Essien, Bryan E., Sundaresan, Sinju, Ocadiz-Ruiz, Ramon, Chavis, Aaron, Tsao, Amy C., Tessier, Arthur J., Hayes, Michael M, Photenhauer, Amanda, Saqui-Salces, Milena, Kang, Anthony J., Shah, Yatrik M., Györffy, Balazs, Merchant, Juanita L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379474/
https://ncbi.nlm.nih.gov/pubmed/27758879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3150
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