ZBP-89 Regulates Expression of Tryptophan Hydroxylase I and Mucosal Defense Against Salmonella Typhimurium in Mice

BACKGROUND & AIMS: ZBP-89 (also ZNF148 or Zfp148) is a butyrate-inducible zinc finger transcription factor that binds to GC-rich DNA elements. Deletion of the N-terminal domain is sufficient to increase mucosal susceptibility to chemical injury and inflammation. We investigated whether condition...

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Main Authors: Essien, Bryan, Grasberger, Helmut, Romain, Rachael D., Law, David J., Veniaminova, Natalia A., Saqui-Salces, Milena, El-Zaatari, Mohamad, Tessier, Arthur, Hayes, Michael M., Yang, Alexander C., Merchant, Juanita L.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665710/
https://ncbi.nlm.nih.gov/pubmed/23395646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.01.057
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