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Synthesis of L-Ascorbyl Flurbiprofenate by Lipase-Catalyzed Esterification and Transesterification Reactions

The synthesis of L-ascorbyl flurbiprofenate was achieved by esterification and transesterification in nonaqueous organic medium with Novozym 435 lipase as biocatalyst. The conversion was greatly influenced by the kinds of organic solvents, speed of agitation, catalyst loading amount, reaction time,...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Xin, Jia-ying, Sun, Li-rui, Chen, Shu-ming, Wang, Yan, Xia, Chun-gu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379130/
https://ncbi.nlm.nih.gov/pubmed/28421196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5751262
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