Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination

Human RAD52 promotes annealing of complementary single-stranded DNA (ssDNA). In-depth knowledge of RAD52-DNA interaction is required to understand how its activity is integrated in DNA repair processes. Here, we visualize individual fluorescent RAD52 complexes interacting with single DNA molecules....

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Brouwer, Ineke, Zhang, Hongshan, Candelli, Andrea, Normanno, Davide, Peterman, Erwin J.G., Wuite, Gijs J.L., Modesti, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379009/
https://ncbi.nlm.nih.gov/pubmed/28329678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.068
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