Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution

During recombinational repair of double-stranded DNA breaks, RAD51 recombinase assembles as a nucleoprotein filament around single-stranded DNA to form a catalytically proficient structure able to promote homology recognition and strand exchange. Mediators and accessory factors guide the action and...

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Bibliografiske detaljer
Main Authors: Candelli, Andrea, Holthausen, Jan Thomas, Depken, Martin, Brouwer, Ineke, Franker, Mariëlla A. M., Marchetti, Margherita, Heller, Iddo, Bernard, Stéphanie, Garcin, Edwige B., Modesti, Mauro, Wyman, Claire, Wuite, Gijs J. L., Peterman, Erwin J. G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210327/
https://ncbi.nlm.nih.gov/pubmed/25288749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307824111
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