Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution

During recombinational repair of double-stranded DNA breaks, RAD51 recombinase assembles as a nucleoprotein filament around single-stranded DNA to form a catalytically proficient structure able to promote homology recognition and strand exchange. Mediators and accessory factors guide the action and...

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Detalhes bibliográficos
Main Authors: Candelli, Andrea, Holthausen, Jan Thomas, Depken, Martin, Brouwer, Ineke, Franker, Mariëlla A. M., Marchetti, Margherita, Heller, Iddo, Bernard, Stéphanie, Garcin, Edwige B., Modesti, Mauro, Wyman, Claire, Wuite, Gijs J. L., Peterman, Erwin J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210327/
https://ncbi.nlm.nih.gov/pubmed/25288749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307824111
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