Herpes simplex virus 1 induces egress channels through marginalized host chromatin

Lytic infection with herpes simplex virus type 1 (HSV-1) induces profound modification of the cell nucleus including formation of a viral replication compartment and chromatin marginalization into the nuclear periphery. We used three-dimensional soft X-ray tomography, combined with cryogenic fluores...

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Publicado en:Sci Rep
Autores principales: Myllys, Markko, Ruokolainen, Visa, Aho, Vesa, Smith, Elizabeth A., Hakanen, Satu, Peri, Piritta, Salvetti, Anna, Timonen, Jussi, Hukkanen, Veijo, Larabell, Carolyn A., Vihinen-Ranta, Maija
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378911/
https://ncbi.nlm.nih.gov/pubmed/27349677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28844
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