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Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery

Parvoviruses are an important platform for gene and cancer therapy. Their cell entry and the following steps, including nuclear import, are inefficient, limiting their use in therapeutic applications. Two models exist on parvoviral nuclear entry: the classical import of the viral capsid using nuclea...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mäntylä, Elina, Aho, Vesa, Kann, Michael, Vihinen-Ranta, Maija
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997771/
https://ncbi.nlm.nih.gov/pubmed/31748386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01532-19
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