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Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery

Parvoviruses are an important platform for gene and cancer therapy. Their cell entry and the following steps, including nuclear import, are inefficient, limiting their use in therapeutic applications. Two models exist on parvoviral nuclear entry: the classical import of the viral capsid using nuclea...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Mäntylä, Elina, Aho, Vesa, Kann, Michael, Vihinen-Ranta, Maija
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997771/
https://ncbi.nlm.nih.gov/pubmed/31748386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01532-19
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