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Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery

Parvoviruses are an important platform for gene and cancer therapy. Their cell entry and the following steps, including nuclear import, are inefficient, limiting their use in therapeutic applications. Two models exist on parvoviral nuclear entry: the classical import of the viral capsid using nuclea...

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Publicat a:J Virol
Autors principals: Mäntylä, Elina, Aho, Vesa, Kann, Michael, Vihinen-Ranta, Maija
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997771/
https://ncbi.nlm.nih.gov/pubmed/31748386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01532-19
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