ZEB1 Induces LOXL2-Mediated Collagen Stabilization and Deposition in the Extracellular Matrix to Drive Lung Cancer Invasion and Metastasis

Lung cancer is the leading cause of cancer-related death, primarily due to distant metastatic disease. Metastatic lung cancer cells can undergo an epithelial-to-mesenchymal transition (EMT) regulated by many transcription factors, including double-negative feedback loop between the microRNA-200 (miR...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Peng, David H., Ungewiss, Christin, Tong, Pan, Byers, Lauren A., Wang, Jing, Canales, Jaime Rodriguez, Villalobos, Pamela A., Uraoka, Naohiro, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio I., Han, Richard I, Wanna, Charles A., Fahrenholtz, Monica, Grande-Allen, Kathryn Jane, Creighton, Chad J., Gibbons, Don L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378666/
https://ncbi.nlm.nih.gov/pubmed/27694892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.358
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