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Computational prediction of the tolerance to amino-acid deletion in green-fluorescent protein

Proteins evolve through two primary mechanisms: substitution, where mutations alter a protein’s amino-acid sequence, and insertions and deletions (indels), where amino acids are either added to or removed from the sequence. Protein structure has been shown to influence the rate at which substitution...

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Publicat a:PLoS One
Autors principals: Jackson, Eleisha L., Spielman, Stephanie J., Wilke, Claus O.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378326/
https://ncbi.nlm.nih.gov/pubmed/28369116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164905
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