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WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3
The compound WP1066 was originally synthesized by modifying the structure of AG490, which inhibits the activation of signal transducer and activator of transcription 3 (STAT3) by directly targeting Janus kinases (JAKs). WP1066 exhibits stronger anti‐cancer activity than AG490 against malignant gliom...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378283/ https://ncbi.nlm.nih.gov/pubmed/28035720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13154 |
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