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STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) regulates the expression of genes that mediate cell survival, proliferation, and angiogenesis and is aberrantly activated in various types of malignancies, including renal cell carcinoma (RCC). We examined whether it could be a n...

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Detalhes bibliográficos
Main Authors: Horiguchi, A, Asano, T, Kuroda, K, Sato, A, Asakuma, J, Ito, K, Hayakawa, M, Sumitomo, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883159/
https://ncbi.nlm.nih.gov/pubmed/20461084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605691
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