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STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) regulates the expression of genes that mediate cell survival, proliferation, and angiogenesis and is aberrantly activated in various types of malignancies, including renal cell carcinoma (RCC). We examined whether it could be a n...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Horiguchi, A, Asano, T, Kuroda, K, Sato, A, Asakuma, J, Ito, K, Hayakawa, M, Sumitomo, M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883159/
https://ncbi.nlm.nih.gov/pubmed/20461084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605691
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