Wird geladen...
In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites
In mouse and human meiosis, DNA double-strand breaks (DSBs) initiate homologous recombination and occur at specific sites called hotspots. The localization of these sites is determined by the sequence-specific DNA binding domain of the PRDM9 histone methyl transferase. Here, we performed an extensiv...
Gespeichert in:
| Veröffentlicht in: | Genome Res |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2017
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378176/ https://ncbi.nlm.nih.gov/pubmed/28336543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.217240.116 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|