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Role of Ectopic Gene Conversion in the Evolution of a Candida krusei Pleiotropic Drug Resistance Transporter Family

Gene duplications enable the evolution of novel gene function, but strong positive selection is required to preserve advantageous mutations in a population. This is because frequent ectopic gene conversions (EGCs) between highly similar, tandem-duplicated, sequences, can rapidly remove fate-determin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Lamping, Erwin, Zhu, Jing-yi, Niimi, Masakazu, Cannon, Richard David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378117/
https://ncbi.nlm.nih.gov/pubmed/28159755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.194811
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