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Order Matters: The Order of Somatic Mutations Influences Cancer Evolution

Cancers evolve as a consequence of multiple somatic lesions, with competition between subclones and sequential subclonal evolution. Some driver mutations arise either early or late in the evolution of different individual tumors, suggesting that the final malignant properties of a subclone reflect t...

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Detaylı Bibliyografya
Yayımlandı:Cold Spring Harb Perspect Med
Asıl Yazarlar: Kent, David G., Green, Anthony R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378012/
https://ncbi.nlm.nih.gov/pubmed/28096247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a027060
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