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Neutral Theory and the Somatic Evolution of Cancer
Kimura’s neutral theory argued that positive selection was not responsible for an appreciable fraction of molecular substitutions. Correspondingly, quantitative analysis reveals that the vast majority of substitutions in cancer genomes are not detectably under selection. Insights from the somatic ev...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5967571/ https://ncbi.nlm.nih.gov/pubmed/29684198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msy079 |
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