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Order Matters: The Order of Somatic Mutations Influences Cancer Evolution
Cancers evolve as a consequence of multiple somatic lesions, with competition between subclones and sequential subclonal evolution. Some driver mutations arise either early or late in the evolution of different individual tumors, suggesting that the final malignant properties of a subclone reflect t...
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| Publicado no: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378012/ https://ncbi.nlm.nih.gov/pubmed/28096247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a027060 |
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