Novel Interconnections in Lipid Metabolism Revealed by Overexpression of Sphingomyelin Synthase-1

This study investigates the consequences of elevating sphingomyelin synthase 1 (SMS1) activity, which generates the main mammalian sphingolipid, sphingomyelin. HepG2 cells stably transfected with SMS1 (HepG2-SMS1) exhibit elevated enzyme activity in vitro and increased sphingomyelin content (mainly...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Deevska, Gergana M., Dotson, Patrick P., Karakashian, Alexander A., Isaac, Giorgis, Wrona, Mark, Kelly, Samuel B., Merrill, Alfred H., Nikolova-Karakashian, Mariana N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377821/
https://ncbi.nlm.nih.gov/pubmed/28087695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.751602
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados