ロード中...
Studies on the Role of Acid Sphingomyelinase and Ceramide in the Regulation of Tumor Necrosis Factor α (TNFα)-converting Enzyme Activity and TNFα Secretion in Macrophages
Acid sphingomyelinase (ASMase) has been proposed to mediate lipopolysaccharide (LPS) signaling in various cell types. This study shows that ASMase is a negative regulator of LPS-induced tumor necrosis factor α (TNFα) secretion in macrophages. ASMase-deficient (asm(−/−)) mice and isolated peritoneal...
保存先:
| 主要な著者: | , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898350/ https://ncbi.nlm.nih.gov/pubmed/20236926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080671 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|