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Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells

During DNA replication in eukaryotic cells, short single-stranded DNA segments known as Okazaki fragments are first synthesized on the lagging strand. The Okazaki fragments originate from ∼35-nucleotide-long RNA-DNA primers. After Okazaki fragment synthesis, these primers must be removed to allow fr...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Liu, Bochao, Hu, Jiazhi, Wang, Jingna, Kong, Daochun
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377794/
https://ncbi.nlm.nih.gov/pubmed/28159842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758599
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