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Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis

Agents that enhance production of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) ameliorate the progression of renal fibrosis. However, the molecular mechanism of this process is not fully understood. We hypothesize that the antifibrotic effects of cGMP and cGMP‐dependent kinase I (cGKI...

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Библиографические подробности
Опубликовано в: :FEBS Open Bio
Главные авторы: Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes‐Peter, Hofmann, Franz, Schlossmann, Jens
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377407/
https://ncbi.nlm.nih.gov/pubmed/28396839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12202
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