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Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis

Agents that enhance production of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) ameliorate the progression of renal fibrosis. However, the molecular mechanism of this process is not fully understood. We hypothesize that the antifibrotic effects of cGMP and cGMP‐dependent kinase I (cGKI...

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Bibliografske podrobnosti
izdano v:FEBS Open Bio
Main Authors: Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes‐Peter, Hofmann, Franz, Schlossmann, Jens
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377407/
https://ncbi.nlm.nih.gov/pubmed/28396839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12202
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